Calcitonin Gene Related Peptide Fragment 8-37 human

Modify Date: 2024-01-08 13:46:31

Calcitonin Gene Related Peptide Fragment 8-37 human Structure
Calcitonin Gene Related Peptide Fragment 8-37 human structure
Common Name Calcitonin Gene Related Peptide Fragment 8-37 human
CAS Number 119911-68-1 Molecular Weight 3125.59000
Density 1.46±0.1 g/cm3 Boiling Point N/A
Molecular Formula C139H230N44O38 Melting Point N/A
MSDS USA Flash Point N/A

 Use of Calcitonin Gene Related Peptide Fragment 8-37 human


HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Sequence: Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe.

 Names

Name CGRP 8-37 (human)
Synonym More Synonyms

  Biological Activity

Description HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Sequence: Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe.
Related Catalog
Target

CGRP receptor[1]

References

[1]. Chiba T, et al. Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol. 1989 Feb;256(2 Pt 1):E331-5.

 Chemical & Physical Properties

Density 1.46±0.1 g/cm3
Molecular Formula C139H230N44O38
Molecular Weight 3125.59000
Exact Mass 3123.74000
PSA 1339.16000
LogP 1.11560
Appearance of Characters powder
Storage condition −20°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles31

More Articles
Calcitonin gene-related peptide stimulates proliferation and osteogenic differentiation of osteoporotic rat-derived bone mesenchymal stem cells.

Mol. Cell Biochem. 402(1-2) , 101-10, (2015)

Osteoporosis, a systemic bone disorder, is prevalent in postmenopausal woman. Bone mesenchymal stem cells (BMSCs), precursors of osteogenic cells, may contribute to prevention or treatment of bone fru...

Intermedin enhances sympathetic outflow via receptor-mediated cAMP/PKA signaling pathway in nucleus tractus solitarii of rats.

Peptides 47 , 1-6, (2013)

Direct administration of intermedin (IMD) into the brain elicits cardiovascular effects different from the systemic administration. Nucleus tractus solitarii (NTS) is an important region for the cardi...

Intermedin in paraventricular nucleus attenuates sympathetic activity and blood pressure via nitric oxide in hypertensive rats.

Hypertension 63(2) , 330-7, (2014)

Intermedin (IMD) is a member of calcitonin/calcitonin gene-related peptide family, which shares the receptor system consisting of calcitonin receptor-like receptor (CRLR) and receptor activity-modifyi...

 Synonyms

FBHuman
CGRP-I 8-37
EINECS 232-693-2
CGRP-I 8-37,HUMAN
MFCD00133153
VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
ALA-CYS-ASN-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-ASP-PHE-LEU-SER-ARG-SER-GLY-GLY-VAL-GLY-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2: ACNTATCVTHRLADFLSRSGGVGKNNFVPTNVGSKAF-NH2DISULFIDE BRIDGE
CYS2-CYS7
HCGRP-(8-37)
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