2-(Hydroxymethyl)isoindoline-1,3-dione

Modify Date: 2024-01-05 16:50:12

2-(Hydroxymethyl)isoindoline-1,3-dione Structure
2-(Hydroxymethyl)isoindoline-1,3-dione structure
Common Name 2-(Hydroxymethyl)isoindoline-1,3-dione
CAS Number 118-29-6 Molecular Weight 177.157
Density 1.5±0.1 g/cm3 Boiling Point 332.0±25.0 °C at 760 mmHg
Molecular Formula C9H7NO3 Melting Point 147-149 °C(lit.)
MSDS Chinese USA Flash Point 154.6±23.2 °C

 Names

Name N-(hydroxymethyl)phthalimide
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 332.0±25.0 °C at 760 mmHg
Melting Point 147-149 °C(lit.)
Molecular Formula C9H7NO3
Molecular Weight 177.157
Flash Point 154.6±23.2 °C
Exact Mass 177.042587
PSA 57.61000
LogP 0.76
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.644

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TI5270000
CHEMICAL NAME :
Phthalimide, N-(hydroxymethyl)-
CAS REGISTRY NUMBER :
118-29-6
BEILSTEIN REFERENCE NO. :
0140946
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H7-N-O3
MOLECULAR WEIGHT :
177.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
DOSE :
300 mg/kg
SEX/DURATION :
female 13 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(10),64,1983

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TI5270000
HS Code 29251995

 Synthetic Route

 Customs

HS Code 2925190090
Summary 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles5

More Articles
Synthesis and anti-inflammatory activity of N-phthalimidomethyl 2,3-dideoxy- and 2,3-unsaturated glycosides.

Carbohydr. Res. 342(9) , 1169-74, (2007)

3,4,6-Tri-O-acetyl-D-galactal, 3,4,6-tri-O-acetyl-D-glucal and 3,6,2',3',4'6'-hexa-O-acetyl-D-lactal were reacted with N-hydroxymethylphthalimide and boron trifluoride etherate to produce the correspo...

Aqueous degradation of N-(hydroxymethyl)phthalimide in the presence of specific and general bases. Kinetic assessment of N-hydroxymethyl derivatives of nitrogen heterocycles as possible prodrugs.

J. Pharm. Biomed. Anal. 7(6) , 685-91, (1989)

The conversion of N-(hydroxymethyl)phthalimide (NHPH) to phthalimide could not be detected within 300 s at pH 9.0, whereas in 0.18 M NaOH complete conversion of NHPH to phthalimide was observed within...

[Effect of hydroxymethylphthalimide on embryogenesis in white rats].

Gig. Sanit. (10) , 64-6, (1983)

 Synonyms

1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-
2-(Hydroxymethyl)-1H-isoindole-1,3(2H)-dione
PHTHALIMIDOMETHANOL
phthalimidomethyl alcohol
oxymethylphthalimide
N-(Hydroxymethyl)phthalimide
N-Hydroxymethylphthalimide
Phthalimidylmethanol
Hydroxymethyl Phthalimide
Methanol,phthalimido
AURORA KA-454
IFLAB-BB F0777-0575
N-Methylolphthalimide
Phthalimide, N- (hydroxymethyl)-
MFCD00005899
EINECS 204-241-4
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