Z-Gly-OH

Modify Date: 2024-01-02 16:48:20

Z-Gly-OH structure	Common Name	Z-Gly-OH
	CAS Number	1138-80-3	Molecular Weight	209.199
	Density	1.3±0.1 g/cm3	Boiling Point	424.0±38.0 °C at 760 mmHg
	Molecular Formula	C₁₀H₁₁NO₄	Melting Point	118-122 °C(lit.)
	MSDS	Chinese USA	Flash Point	210.2±26.8 °C

Use of Z-Gly-OH

Z-Glycine is a Glycine (HY-Y0966) derivative[1].

Name	N-benzyloxycarbonylglycine
Synonym	More Synonyms

Description	Z-Glycine is a Glycine (HY-Y0966) derivative[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References	[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Density	1.3±0.1 g/cm3
Boiling Point	424.0±38.0 °C at 760 mmHg
Melting Point	118-122 °C(lit.)
Molecular Formula	C₁₀H₁₁NO₄
Molecular Weight	209.199
Flash Point	210.2±26.8 °C
Exact Mass	209.068802
PSA	75.63000
LogP	1.37
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.554
Water Solubility	methanol: 0.1 g/mL, clear

Z-Gly-OH MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9129000

CHEMICAL NAME :: Glycine, N-carboxy-, N-benzyl ester

CAS REGISTRY NUMBER :: 1138-80-3

BEILSTEIN REFERENCE NO. :: 0526877

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H11-N-O4

MOLECULAR WEIGHT :: 209.22

WISWESSER LINE NOTATION :: QVN1R&1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravaginal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 280 mg/kg

SEX/DURATION :: female 28 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravaginal

DOSE :: 280 mg/kg

SEX/DURATION :: female 28 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 70,60,1981

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Risk Phrases	R62
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	MB9129000
HS Code	2924299090

Precursor 7
CAS#:501-53-1 Benzyl chloroformate CAS#:56-40-6 Glycine CAS#:77987-49-6 Benzyl N-(2-Hyd... CAS#:21855-71-0 Z-Gly-NHNHPh
CAS#:1145-81-9 N-Cbz-glycine E... CAS#:16881-32-6 N-(Benzyloxycar... CAS#:5513-38-2 benzyl N-benzyl...
DownStream 10
CAS#:3589-41-1 Benzyl (cyanome... CAS#:15050-24-5 benzyl N-(2-chl... CAS#:14131-92-1 L-Phenylalanine... CAS#:949-90-6 z-gly-nh2
CAS#:39608-31-6 Z-Sar-OH CAS#:1738-68-7 BENZYL2-AMINOAC... CAS#:19525-53-2 benzyl 2-[(2-ph... CAS#:17942-42-6 L-Phenylalanine...
CAS#:21855-72-1 BENZYL (2-(METH... CAS#:100-39-0 Benzyl bromide

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration.

Neuroreport 5(7) , 777-80, (1994)

Although glycine does not cross easily the blood-brain barrier, it exhibits at very high doses (10-40 mmol kg-1) a modest anticonvulsant activity. In this study, carbamate derivatives--N-benzyloxycarb...

Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine alpha-hydroxylating monooxygenase (PHM).

Bioorg. Med. Chem. 16 , 10061-74, (2008)

Peptidyl alpha-hydroxylating monooxygenase (PHM) functions in vivo towards the biosynthesis of alpha-amidated peptide hormones in mammals and insects. PHM is a potential target for the development of ...

Synthesis and anticonvulsant activity of N-benzyloxycarbonyl-amino acid prodrugs of phenytoin.

J. Pharm. Pharmacol. 51 , 549-553, (1999)

Glycine, which has weak anticonvulsant properties, has been shown to potentiate the activity of several antiepileptic drugs but not phenytoin. Recently, studies have shown that N-(benzyloxycarbonyl)gl...

Cbz-Gly-OH

CBZ-GLYCINE

QV1MVO1R

N-[(Benzyloxy)carbonyl]glycine

N-Carbobenzoxyglycine

Z-GLY-OH

CBZ-GLY

N-Carbobenzyloxyglycine

Z-GLYCINE

Glycine, N-[(phenylmethoxy)carbonyl]-

z-gly

benzyloxycarbonylaminomethylcarboxylic acid

EINECS 214-516-0

MFCD00002691

N-Gly-OH

N-Cbz-glycine

Carbobenzyloxyglycine

{[(Benzyloxy)carbonyl]amino}acetic acid

Benzyloxycarbonylglycine

Benzyloxycarbonyl-glycine

GL Biochem (Shanghai) Ltd.
China
Product Name: Z-Gly-OH
Price: $Inquiry/1kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Z-Gly-OH
Price: ￥198.0/100g ￥638.0/500g
Purity: 95.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: N-Benzyloxycarbonylglycine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Nanjing Peptide Biotech Ltd
China
Product Name: Z-Gly-OH
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-Carbobenzyloxyglycine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Henan Tianfu Chemical Co., Ltd.
China
Product Name: TIANFU CHEM 1138-80-3 N-Carbobenzyloxyglycine
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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