(r,s)-n-nitrosoanabasine

Modify Date: 2024-01-06 10:23:07

(r,s)-n-nitrosoanabasine Structure
(r,s)-n-nitrosoanabasine structure
Common Name (r,s)-n-nitrosoanabasine
CAS Number 1133-64-8 Molecular Weight 191.23000
Density 1.24g/cm3 Boiling Point 380.2ºC at 760mmHg
Molecular Formula C10H13N3O Melting Point N/A
MSDS N/A Flash Point 9℃
Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger

 Names

Name (r,s)-n-nitrosoanabasine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 380.2ºC at 760mmHg
Molecular Formula C10H13N3O
Molecular Weight 191.23000
Flash Point 9℃
Exact Mass 191.10600
PSA 45.56000
LogP 2.22790
Vapour Pressure 1.21E-05mmHg at 25°C
Index of Refraction 1.624
Storage condition ?20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV4550000
CHEMICAL NAME :
Anabasine, 1-nitroso-
CAS REGISTRY NUMBER :
1133-64-8
LAST UPDATED :
199506
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H13-N3-O
MOLECULAR WEIGHT :
191.26
WISWESSER LINE NOTATION :
T6NTJ ANO B- CT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6000 mg/kg/50W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 18,265,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1030 mg/kg/7W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 71,25,1993

 Safety Information

Symbol GHS02 GHS06 GHS08
GHS02, GHS06, GHS08
Signal Word Danger
Hazard Statements H225-H301 + H311 + H331-H370
Precautionary Statements P210-P260-P280-P301 + P310-P311
Hazard Codes F,T
Risk Phrases 11-23/24/25-39/23/24/25
Safety Phrases 7-16-36/37-45
RIDADR UN1230 - class 3 - PG 2 - Methanol, solution
HS Code 2933990090

 Synthetic Route

~%

(r,s)-n-nitrosoanabasine Structure

(r,s)-n-nitroso...

CAS#:1133-64-8

Literature: Chemische Berichte, , vol. 64, p. 266,273

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles10

More Articles
Oral mucosal changes and nicotine disposition in users of Swedish smokeless tobacco products: a comparative study.

J. Oral. Pathol. Med. 23(4) , 161-7, (1994)

The purpose of this study was to investigate the uptake and metabolism of nicotine by smokeless (oral) tobacco users and to find out if the less pronounced clinical changes in the oral mucosa in users...

N'-Nitrosoanabasine (NAB).

IARC Monogr. Eval. Carcinog. Risk Chem. Hum. 37 , 225-31, (1985)

Immunotoxic effects of smokeless tobacco on the accessory cell function of rat oral epithelium.

Eur. J. Oral Sci. 105(1) , 45-51, (1997)

Smokeless tobacco (ST) is known to adversely effect the oral mucosa, but knowledge about the influence on immune defence is limited. Few studies have investigated the effect of ST on the local immune ...

 Synonyms

n-nitrosoanabasine
3-(1-nitroso-2-piperidyl)pyridine
1-nitrosoanabasine
(s)-3-(1-nitroso-2-piperidinyl)pyridine
MFCD01081833
(S)-1-Nitroso-1,2,3,4,5,6-hexahydro-[2,3']bipyridyl
3-(1-nitrosopiperidin-2-yl)pyridine
1-nitroso-anabasin
3-[(2S)-1-Nitroso-2-piperidinyl]pyridine
(S)-N-Nitroso Anabasine