Glycine Anhydride

Modify Date: 2024-01-02 23:44:04

Glycine Anhydride Structure
Glycine Anhydride structure
Common Name Glycine Anhydride
CAS Number 106-57-0 Molecular Weight 114.103
Density 1.2±0.1g/cm3 Boiling Point 573.7±43.0°C at 760 mmHg
Molecular Formula C4H6N2O2 Melting Point 300°C
MSDS Chinese USA Flash Point 301.9±28.3°C

 Names

Name piperazine-2,5-dione
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1g/cm3
Boiling Point 573.7±43.0°C at 760 mmHg
Melting Point 300°C
Molecular Formula C4H6N2O2
Molecular Weight 114.103
Flash Point 301.9±28.3°C
Exact Mass 114.042931
PSA 58.20000
LogP -2.93
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.649
Storage condition 2~8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6325250
CHEMICAL NAME :
2,5-Piperazinedione
CAS REGISTRY NUMBER :
106-57-0
BEILSTEIN REFERENCE NO. :
0112112
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C4-H6-N2-O2
MOLECULAR WEIGHT :
114.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,227,1954

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TL6325250
HS Code 2933599090

 Synthetic Route

 Customs

HS Code 2933599090
Summary 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles8

More Articles
Design and synthesis of novel soluble 2,5-diketopiperazine derivatives as potential anticancer agents.

Eur. J. Med. Chem. 83 , 236-44, (2014)

Non-protected 2,5-diketopiperazine derivatives have poor solubility thus with negative impact on their bioavailability. In the present study, twenty-one novel soluble mono-protected, and three non-pro...

Rational design and combinatorial evaluation of enzyme inhibitor scaffolds: identification of novel inhibitors of matrix metalloproteinases.

J. Med. Chem. 41(13) , 2194-200, (1998)

The discovery of a novel series of heterocyclic matrix metalloproteinase (MMPs) inhibitors is described. Published crystal structures of peptidyl hydroxamates bound to MMPs were the basis for the rati...

Diagnostic NH and OH vibrations for oxazolone and diketopiperazine structures: b2 from protonated triglycine.

J. Am. Soc. Mass Spectrom. 22 , 1197-1203, (2011)

We present infrared multiple photon dissociation (IRMPD) spectra in the hydrogen stretching region of the simplest b fragment, b(2) from protonated triglycine, contrasted to that of protonated cyclo(G...

 Synonyms

piperazine-2,5-dione
EINECS 203-411-5
Glycocoll Anhydride
Cyclodiglycine
2,5-Diketopiperazine
2,5-Pyrazinediol, 3,6-dihydro-
3,6-Dihydro-2,5-pyrazinediol
5-24-05-00294 (Beilstein Handbook Reference)
2,5-Piperazinedione
Glycine Anhydride
Diglycolyldiamide
MFCD00006009
a,g-Diacipiperazine
Cycloglycylglycine
2,5-Dioxopiperazine
Oxiracetam Impurity 2
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