(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine

Modify Date: 2024-01-02 07:17:50

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Structure
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine structure
Common Name (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
CAS Number 105812-81-5 Molecular Weight 223.286
Density 1.1±0.1 g/cm3 Boiling Point 300.3±42.0 °C at 760 mmHg
Molecular Formula C13H18FNO Melting Point 97-101ºC
MSDS USA Flash Point 135.4±27.9 °C

 Names

Name (3S,4R)-4-(4-Fluorophenyl)-3-Hydroxymethyl-1-Methylpiperidine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 300.3±42.0 °C at 760 mmHg
Melting Point 97-101ºC
Molecular Formula C13H18FNO
Molecular Weight 223.286
Flash Point 135.4±27.9 °C
Exact Mass 223.137238
PSA 23.47000
LogP 1.66
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.518

 Safety Information

Hazard Codes Xn:Harmful
Risk Phrases R22;R41;R51/53
Safety Phrases S22-S26-S39-S61
RIDADR UN3077
Packaging Group III
Hazard Class 9
HS Code 2933399090

 Synthetic Route

~77%

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Structure

(3S,4R)-4-(4-Fl...

CAS#:105812-81-5

Literature: WO2004/5254 A1, ; Page 9 ;

~81%

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Structure

(3S,4R)-4-(4-Fl...

CAS#:105812-81-5

Literature: Tetrahedron Asymmetry, , vol. 22, # 1 p. 1 - 3

~%

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Structure

(3S,4R)-4-(4-Fl...

CAS#:105812-81-5

Literature: WO2005/63707 A1, ; Page 30 ;

~%

(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine Structure

(3S,4R)-4-(4-Fl...

CAS#:105812-81-5

Literature: Tetrahedron Asymmetry, , vol. 22, # 1 p. 1 - 3

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinemethanol
[(3S,4R)-4-(4-Fluorophenyl)-1-methyl-3-piperidinyl]methanol
(3S,4R)-4-(4′-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
(3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
EINECS 406-030-4
MFCD06658161
UNII:QRA30YT0AV
(-)-trans-4-(4-Fluorophenyl)-3-hydroxymethyl-N-methylpiperidine
(3S)-4-(4'-Fluorophenyl)-3-hydroxymethyl-1-methylpiperidine
trans-(-)-4-FLUOROPHENYL)-1; -METHYL-3-PIPERIDINE METHANOL
[(3S,4R)-4-(4-Fluorophenyl)-1-methylpiperidin-3-yl]methanol
3-Piperidinemethanol, 4-(4-fluorophenyl)-1-methyl-, (3S,4R)-
Paroxetine Impurity 11
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