N,O-Bis(trimethylsilyl)acetamide

Modify Date: 2024-01-02 22:42:37

N,O-Bis(trimethylsilyl)acetamide Structure
N,O-Bis(trimethylsilyl)acetamide structure
Common Name N,O-Bis(trimethylsilyl)acetamide
CAS Number 10416-59-8 Molecular Weight 203.429
Density 0.8±0.1 g/cm3 Boiling Point 162.1±0.0 °C at 760 mmHg
Molecular Formula C8H21NOSi2 Melting Point 24 °C
MSDS Chinese USA Flash Point 65.5±22.6 °C
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

 Names

Name N,O-Bis(trimethylsilyl)acetamide
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 162.1±0.0 °C at 760 mmHg
Melting Point 24 °C
Molecular Formula C8H21NOSi2
Molecular Weight 203.429
Flash Point 65.5±22.6 °C
Exact Mass 203.116165
PSA 21.59000
LogP 3.16
Vapour Pressure 2.9±0.3 mmHg at 25°C
Index of Refraction 1.411
Storage condition 0-6°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AK3000000
CHEMICAL NAME :
Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester
CAS REGISTRY NUMBER :
10416-59-8
LAST UPDATED :
199707
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H21-N-O-Si2
MOLECULAR WEIGHT :
203.48
WISWESSER LINE NOTATION :
1-SI-1&1&OY1&UN-SI-1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Immunological Including Allergic - decreased immune response
REFERENCE :
StoGD# Personal Communication from G.D. Stoner, Dept. of Community Medicine, School of Medicine, Univ. of California, La Jolla, CA 92037, May 25, 1975 Volume(issue)/page/year: 27MAY1975 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg/I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,495,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7061 No. of Facilities: 10 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 226 (estimated) No. of Female Employees: 151 (estimated)

 Safety Information

Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger
Hazard Statements H226-H302-H314
Supplemental HS Reacts violently with water.
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes C:Corrosive
Risk Phrases R10;R14;R22;R34
Safety Phrases S26-S36/37/39-S45-S7/8-S43A-S36-S30
RIDADR UN 2920 8/PG 2
WGK Germany 3
RTECS AK3000000
Packaging Group II
Hazard Class 8
HS Code 29310095

 Synthetic Route

~77%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Literature: Atofina Patent: US6335456 B1, 2002 ; Location in patent: Example 3 ;

~%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Literature: Atofina Patent: US6335456 B1, 2002 ; Location in patent: Example 6 ;

~%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Literature: Journal of the American Chemical Society, , vol. 88, p. 3390 - 3395

~%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Detail
Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 5 p. 1009 - 1013,891 - 894

~%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Detail
Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 5 p. 1009 - 1013,891 - 894

~%

N,O-Bis(trimethylsilyl)acetamide Structure

N,O-Bis(trimeth...

CAS#:10416-59-8

Detail
Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 53, # 5 p. 1009 - 1013,891 - 894

 Customs

HS Code 2931900090
Summary 2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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 Synonyms

TMS-BABSA
bsa kit
EINECS 233-892-7
tms-ba kit
MFCD00008270
N,O-Bis(trimethylsilyl)acetamide
Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester, (1E)-
TMS-BA
Trimethylsilyl N-(trime
TMS-BA KitBSA Kit
CB2500
Trimethylsilyl (1E)-N-(trimethylsilyl)ethanimidoate
bis-TMS-acetamide
BSA
dynasylan bsa
Trimethylsilyl (1E)-N-(trimethylsilyl)ethanimidate
(E)-Trimethylsilyl N-(trimethylsilyl)acetimidate
Trimethylsilyl N-(trimethylsilyl)acetimidate
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