Ethylenediaminetetraacetic acid sodium hydrate

Modify Date: 2024-01-02 10:38:09

Ethylenediaminetetraacetic acid sodium hydrate Structure
Ethylenediaminetetraacetic acid sodium hydrate structure
Common Name Ethylenediaminetetraacetic acid sodium hydrate
CAS Number 10378-23-1 Molecular Weight 416.201
Density N/A Boiling Point 614.2ºC at 760mmHg
Molecular Formula C10H16N2Na4O10 Melting Point >300ºC
MSDS Chinese USA Flash Point 325.2ºC
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

 Use of Ethylenediaminetetraacetic acid sodium hydrate


Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can also decrease the formation of disulfide bonds[1][2][3].

 Names

Name Ethylenediaminetetraacetic acid tetrasodium salt dihydrate
Synonym More Synonyms

  Biological Activity

Description Ethylenediaminetetraacetic acid (EDTA) sodium hydrate is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid sodium hydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid sodium hydrate can also decrease the formation of disulfide bonds[1][2][3].
Related Catalog
References

[1]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9.

[2]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45(5):565-76.

[3]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10(1):58-62.

 Chemical & Physical Properties

Boiling Point 614.2ºC at 760mmHg
Melting Point >300ºC
Molecular Formula C10H16N2Na4O10
Molecular Weight 416.201
Flash Point 325.2ºC
Exact Mass 416.039581
PSA 185.46000
Storage condition Store at RT.
Water Solubility H2O: clear, colorless

 Safety Information

Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger
Hazard Statements H302-H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36/37
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS DB6145180
HS Code 29224995

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 Synonyms

Ethylenediaminetetraacetic acid tetrasodium salt
Sodium 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetraacetate hydrate (4:1:2)
Ethylenediaminetetraacetic Acid Tetrasodium Salt Dihydrate
EDTA 4Na Dihydrate
Tetrasodium ethylenediaminetetraacetate dihydrate
Sodium 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate hydrate (4:1:2)
EDTA-4Na.2H2O
EDTA tetrasodium salt
EINECS 208-924-8
MFCD00007499
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