4-Oxo-2-nonenal

Modify Date: 2024-01-05 23:33:06

4-Oxo-2-nonenal structure	Common Name	4-Oxo-2-nonenal
	CAS Number	103560-62-9	Molecular Weight	154.206
	Density	0.9±0.1 g/cm3	Boiling Point	258.1±23.0 °C at 760 mmHg
	Molecular Formula	C₉H₁₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	95.2±19.6 °C

Use of 4-Oxo-2-nonenal

(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist[1][2][3].

Name	(E)-4-oxonon-2-enal
Synonym	More Synonyms

Description	(E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist[1][2][3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cardiovascular Disease
References	[1]. S H Lee, et al. Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem Res Toxicol. 2000 Aug;13(8):698-702. [2]. Fumie Saito, et al. Reaction products of gamma-tocopherol with (E)-4-oxo-2-nonenal in acidic acetonitrile. Biosci Biotechnol Biochem. 2010;74(1):168-74. [3]. Rabea Graepel, et al. 4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo. J Pharmacol Exp Ther. 2011 Apr;337(1):117-24.

Description

Related Catalog

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Cardiovascular Disease

References

[1]. S H Lee, et al. Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation. Chem Res Toxicol. 2000 Aug;13(8):698-702.

[2]. Fumie Saito, et al. Reaction products of gamma-tocopherol with (E)-4-oxo-2-nonenal in acidic acetonitrile. Biosci Biotechnol Biochem. 2010;74(1):168-74.

[3]. Rabea Graepel, et al. 4-oxo-2-nonenal (4-ONE): evidence of transient receptor potential ankyrin 1-dependent and -independent nociceptive and vasoactive responses in vivo. J Pharmacol Exp Ther. 2011 Apr;337(1):117-24.

Density	0.9±0.1 g/cm3
Boiling Point	258.1±23.0 °C at 760 mmHg
Molecular Formula	C₉H₁₄O₂
Molecular Weight	154.206
Flash Point	95.2±19.6 °C
Exact Mass	154.099380
PSA	34.14000
LogP	1.59
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.446

Precursor 9
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CAS#:66-25-1 Hexanal
DownStream 2
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