22425-82-7
22425-82-7 structure
- Name: methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
- Chemical Name: methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
- CAS Number: 22425-82-7
- Molecular Formula: C31H50O4
- Molecular Weight: 486.72600
- Catalog: Signaling Pathways GPCR/G Protein Adrenergic Receptor
- Create Date: 2018-07-14 11:27:27
- Modify Date: 2024-01-07 18:07:24
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Methyl maslinate is a β-adrenergic antagonist. Methyl maslinate is a potent cardiotonic and antidysrhythmic agent. Methyl maslinate has the potential for hypertension research[1].
| Name | methyl (4aS,6aR,6aS,6bR,10R,11R,12aR,14bR)-10,11-dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate |
|---|---|
| Synonyms |
Crategolic acid methyl ester
Methyl maslinate Maslinic acid methyl ester 2alpha,3beta-Dihydroxyolean-12-en-28-oic acid methyl ester |
| Description | Methyl maslinate is a β-adrenergic antagonist. Methyl maslinate is a potent cardiotonic and antidysrhythmic agent. Methyl maslinate has the potential for hypertension research[1]. |
|---|---|
| Related Catalog | |
| In Vivo | Methyl maslinate (MM) (20-60 mg/kg; i.p.) shows significant, dose-dependent vasodepressor effect and sinus bradycardia, lasting more than 60 minutes with a maximum at 20 minutes, and shows potent hymodynamic effect[1]. Methyl maslinate (40 mg/kg) shows antidysrhythmic activity on ischemia-reperfusion dysrhythmia[1]. Animal Model: Wistar male rats (300-320 g)[1] Dosage: 20-60 mg/kg Administration: Intraperitoneal injection; once Result: Showed significant, dose-response vasodepressor effect and sinus bradicardia. Antagonized β-Adrenergic. Showed antidysrhythmic activity. |
| References |
| Density | 1.11g/cm3 |
|---|---|
| Boiling Point | 541.9ºC at 760mmHg |
| Molecular Formula | C31H50O4 |
| Molecular Weight | 486.72600 |
| Flash Point | 163.1ºC |
| Exact Mass | 486.37100 |
| PSA | 66.76000 |
| LogP | 6.29280 |
| Vapour Pressure | 5.29E-14mmHg at 25°C |
| Index of Refraction | 1.552 |
| Precursor 0 | |
|---|---|
| DownStream 4 | |
