51213-99-1

51213-99-1 structure

Name: Clanfenur
Chemical Name: Clanfenur
CAS Number: 51213-99-1
Molecular Formula: C₁₆H₁₅ClFN₃O₂
Molecular Weight: 335.76
Catalog: Signaling Pathways Cell Cycle/DNA Damage Microtubule/Tubulin
Create Date: 2018-08-08 11:41:14
Modify Date: 2024-01-14 17:07:09
Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].

Name	Clanfenur
Synonyms	1-(2-Dimethylaminoethyl)-piperazine dimethyl(2-piperazinylethyl)amine 1-(2-N,N-dimethylamino-6-fluorobenzoyl)-3-(4-chlorophenyl)urea N,N-Dimethyl-2-(piperazin-1-yl)ethanamine N-(CH2)2NMe2-piperazine 4-(2-dimethylaminoethyl)piperazine dimethyl(2-piperazin-1-yl-ethyl)amine N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamide 1-(2-N,N-dimethyl)-ethylpiperazine

Description	Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References	[1]. J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95.

HS Code	2924299090

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%