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485-65-4

485-65-4 structure
485-65-4 structure

Name hydrocinchonine
Synonyms MFCD00216716
(1S)-((2R,4S,5R)-5-Ethylquinuclidin-2-yl)(quinolin-4-yl)methanol
EINECS 207-621-8
10,11-dihydro-cinchonan-9-ol
Cinconifine
Description Hydrocinchonine (Dihydrocinchonine) is a multidrug resistance (MDR)-reversal agent. Hydrocinchonine exerts synergistic apoptotic effect with Paclitaxel in MES-SA/DX5 cells[1].
Related Catalog
References

[1]. Sang-Yun Lee, et al. Hydrocinchonine, cinchonine, and quinidine potentiate paclitaxel-induced cytotoxicity and apoptosis via multidrug resistance reversal in MES-SA/DX5 uterine sarcoma cells. Environ Toxicol. 2011 Aug;26(4):424-31.  

Density 1.18 g/cm3
Boiling Point 467.1ºC at 760 mmHg
Melting Point 269 - 272ºC
Molecular Formula C19H24N2O
Molecular Weight 296.40700
Flash Point 236.3ºC
Exact Mass 296.18900
PSA 36.36000
LogP 3.32650
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.639
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases 36/37
RIDADR NONH for all modes of transport
WGK Germany 3