53446-10-9

53446-10-9 structure

Name: 3-cysteinylacetaminophen, trifluoroacetic acid salt
Chemical Name: (2R)-3-(5-acetamido-2-hydroxyphenyl)sulfanyl-2-aminopropanoic acid
CAS Number: 53446-10-9
Molecular Formula: C₁₁H₁₄N₂O₄S
Molecular Weight: 270.30
Catalog: Biochemical Amino acids and their derivatives Cysteine derivative
Create Date: 2018-11-24 18:44:32
Modify Date: 2024-04-02 17:22:14
Paracetamol-cysteine is a Paracetamol-cysteine Paracetamol protein adduct (PPA) and is formed when paracetamol is oxidized to the reactive metabolite N-acetyl-p-benzoquinoneimine (NAPQI)[1].

Name	(2R)-3-(5-acetamido-2-hydroxyphenyl)sulfanyl-2-aminopropanoic acid
Synonyms	UNII-6Q2X58Y8BP 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt 3-(Cystein-S-yl)paracetamol 3-(Cystein-S-yl)acetaminophen L-Cysteine,S-[5-(acetylamino)-2-hydroxyphenyl]

Description	Paracetamol-cysteine is a Paracetamol-cysteine Paracetamol protein adduct (PPA) and is formed when paracetamol is oxidized to the reactive metabolite N-acetyl-p-benzoquinoneimine (NAPQI)[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Kennon Heard, et al. Paracetamol (acetaminophen) protein adduct concentrations during therapeutic dosing. Br J Clin Pharmacol. 2016 Mar;81(3):562-8.

Density	1.44g/cm3
Boiling Point	541.1ºC at 760mmHg
Melting Point	190-193ºC dec.
Molecular Formula	C₁₁H₁₄N₂O₄S
Molecular Weight	270.30
Flash Point	281ºC
Exact Mass	384.06000
PSA	175.25000
LogP	2.26120
Index of Refraction	1.654
Storage condition	Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability	Hygroscopic