CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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KG7550000
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CHEMICAL NAME :
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Estra-1,3,5(10)-triene-16-beta,17-beta-diol, 3-methoxy-16-methyl-
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CAS REGISTRY NUMBER :
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5108-94-1
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C20-H28-O3
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MOLECULAR WEIGHT :
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316.48
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WISWESSER LINE NOTATION :
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L E5 B666TTT&J E1 FQ GQ G1 OO1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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35 mg/kg
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SEX/DURATION :
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female 35 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
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REFERENCE :
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ENDOAO Endocrinology (Baltimore). (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21203) V.1- 1917- Volume(issue)/page/year: 63,561,1958
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Unreported
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DOSE :
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30 mg/kg
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SEX/DURATION :
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female 30 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Maternal Effects - uterus, cervix, vagina
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REFERENCE :
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RPHRA6 Recent Progress In Hormone Research. Proceedings of the Laurentian Hormone Conference. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1947- Volume(issue)/page/year: 20,395,1964
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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12 mg/kg
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SEX/DURATION :
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female 4-6 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
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REFERENCE :
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JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 9,277,1965
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