148857-42-5

148857-42-5 structure

Name: (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione
Chemical Name: 2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
CAS Number: 148857-42-5
Molecular Formula: C₁₁H₁₀ClNO₃
Molecular Weight: 239.655
Create Date: 2016-08-13 19:41:06
Modify Date: 2024-01-12 17:59:15

Name	2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione
Synonyms	3-chloro-1-phenylmethylamino-2-hydroxypropane N-(3-chloro-2-hydroxypropyl)phthalimide (-)-2-(3-chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione 1-(N-benzyl)amino-3-chloro-2-propanol (RS)-1-chloro-3-phthalimidopropan-2-ol 1-(benzylamino)-3-chloro-2-propanol 1-chloro-3-benzylpropan-2-ol 2-Propanol,1-chloro-3-[(phenylmethyl)amino] (+/-)-1-chloro-3-phthalimido-2-propanol (S)-1-phthalimido-3-chloro-2-propanol 1H-Isoindole-1,3(2H)-dione, 2-[(2S)-3-chloro-2-hydroxypropyl]- 2-[(2S)-3-Chloro-2-hydroxypropyl]-1H-isoindole-1,3(2H)-dione rac-1-phthalimido-3-chloro-2-propanol N-(3-chloro-2-hydroxypropyl)benzylamine 1-(benzylamino)-3-chloropropan-2-ol N-benzyl-3-chloro-2-hydroxypropylamine 3-(Benzylamino)-1-chloro-2-propanol (S)-2-(3-chloro-2-hydroxypropyl)isoindoline-1,3-dione Rivaroxaban Impurity 53

Density	1.4±0.1 g/cm3
Boiling Point	405.4±35.0 °C at 760 mmHg
Molecular Formula	C₁₁H₁₀ClNO₃
Molecular Weight	239.655
Flash Point	199.0±25.9 °C
Exact Mass	239.034927
PSA	57.61000
LogP	1.63
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.616

Hazard Codes	T+

136918-14-4

67843-74-7

~74%

148857-42-5

Literature: Tammana, Rajesh; Vemula, Kiran Kumar; Guruvindapalli, Ramadasu; Yanamandr, Ramesh; Gutta, Madhusudhan Arkivoc, 2012 , vol. 2012, # 6 p. 45 - 56

136918-14-4

67843-74-7

1074-82-4

148857-42-5

Literature: Pharmacia and Upjohn Company Patent: US6362334 B1, 2002 ; Location in patent: Example 4 ;

136918-14-4

51594-55-9

~82%

161596-47-0

148857-42-5

Literature: Pace, Vittorio; Hoyos, Pilar; Fernandez, Maria; Sinisterra, Jose V.; Alcantara, Andres R. Green Chemistry, 2010 , vol. 12, # 8 p. 1380 - 1382

1074-82-4

148857-42-5

Literature: Martinez Lagos, Fernando; Carballeira, Jose D.; Bermudez, Jose L.; Alvarez, Emilio; Sinisterra, Jose V. Tetrahedron Asymmetry, 2004 , vol. 15, # 5 p. 763 - 770

Precursor 3
67843-74-7 1074-82-4 51594-55-9
DownStream 2
168828-89-5 161596-47-0

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4