154540-49-5

154540-49-5 structure

Name: Fluoroclebopride
Chemical Name: Fluoroclebopride
CAS Number: 154540-49-5
Molecular Formula: C₂₀H₂₃ClFN₃O₂
Molecular Weight: 391.867
Catalog: Signaling Pathways GPCR/G Protein Dopamine Receptor
Create Date: 2016-06-20 00:14:42
Modify Date: 2024-01-09 12:49:17
Fluoroclebopride binds reversibly to dopamine receptors. 18F labeled fluoroclebopride has been used as a probe for studying D2/D3 receptor availability via PET in various monkey models[1][2].

Name	Fluoroclebopride
Synonyms	4-AMINO-5-CHLORO-N-(1-((4-FLUOROPHENYL)METHYL)-PIPERIDIN-4-YL)-2-METHOX YBENZAMIDE 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methoxybenzamide 4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]piperidin-4-yl]-2-methoxybenzamide 4-amino-5-chloro-N-[1-(4-fluorobenzyl)piperidin-4-yl]-2-methoxybenzamide Benzamide, 4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy- 4-Amino-5-chloro-N-[1-(4-fluorobenzyl)-4-piperidinyl]-2-methoxybenzamide

Description	Fluoroclebopride binds reversibly to dopamine receptors. 18F labeled fluoroclebopride has been used as a probe for studying D2/D3 receptor availability via PET in various monkey models[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Nader MA, Czoty PW. PET imaging of dopamine D2 receptors in monkey models of cocaine abuse: genetic predisposition versus environmental modulation. Am J Psychiatry. 2005 Aug;162(8):1473-82. [2]. Czoty PW, et al. Effects of repeated treatment with the dopamine D2/D3 receptor partial agonist aripiprazole on striatal D2/D3 receptor availability in monkeys. Psychopharmacology (Berl). 2013 Sep 29:10.1007/s00213-013-3274-7.