301225-40-1
301225-40-1 structure
- Name: TERT-BUTYL 4-(2-PYRIMIDINYLAMINO)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE
- Chemical Name: tert-butyl 4-(pyrimidin-2-ylamino)piperidine-1-carboxylate
- CAS Number: 301225-40-1
- Molecular Formula: C14H22N4O2
- Molecular Weight: 278.35000
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyrimidine compound Amine
- Create Date: 2017-01-08 15:35:19
- Modify Date: 2024-02-04 11:36:42
| Name | tert-butyl 4-(pyrimidin-2-ylamino)piperidine-1-carboxylate |
|---|---|
| Synonyms |
4-N-(pyrimid-2-yl)amino-1-tert-butoxycarbonylpiperidine
4-(N-(pyrimidin-2-yl)amino)-1-t-butoxycarbonylpiperidine tert-butyl-4-(pyrimidin-2-ylamino)-1-piperidinecarboxylate Tert-Butyl 4-(2-Pyrimidinylamino)Tetrahydro-1(2H)-Pyridinecarboxylate |
| Melting Point | 132-133°C |
|---|---|
| Molecular Formula | C14H22N4O2 |
| Molecular Weight | 278.35000 |
| Exact Mass | 278.17400 |
| PSA | 67.35000 |
| LogP | 2.29890 |
| HS Code | 2933990090 |
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~63%
301225-40-1 |
| Literature: BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG Patent: WO2007/106705 A1, 2007 ; Location in patent: Page/Page column 102 ; WO 2007/106705 A1 |
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301225-40-1 |
| Literature: Willoughby, Christopher A.; Rosauer, Keith G.; Hale, Jeffery J.; Budhu, Richard J.; Mills, Sander G.; Chapman, Kevin T.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 427 - 431 |
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301225-40-1 |
| Literature: Willoughby, Christopher A.; Rosauer, Keith G.; Hale, Jeffery J.; Budhu, Richard J.; Mills, Sander G.; Chapman, Kevin T.; MacCoss, Malcolm; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 427 - 431 |
| Precursor 4 | |
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| DownStream 1 | |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |