67526-94-7

67526-94-7 structure

Name: Hexanoic acid, 6-(acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3, 3a-dihydroxy-3,6, 9-trimethyl-8-[(2-methyl-1-oxo-2-butenyl)oxy]-2-oxo-4-(1-oxobutoxy )azuleno[4,5-b]furan-7-yl ester, [3R-[3.alpha.,3a.
Chemical Name: thapsigargicin
CAS Number: 67526-94-7
Molecular Formula: C₃₂H₄₆O₁₂
Molecular Weight: 622.70
Catalog: Research Areas Inflammation/Immunology
Create Date: 2017-09-27 00:34:53
Modify Date: 2024-01-10 06:56:01
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets[1].

Name	thapsigargicin
Synonyms	MFCD00214081

Description	Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Ali H, et al. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol. 1985 Jul;85(3):705-12.

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H332
Precautionary Statements	P280
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	S26;S36
RIDADR	NONH for all modes of transport