Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Price: ￥108.0/5g ￥358.0/25g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

2328-12-3

2328-12-3 structure

Name: 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride
Chemical Name: 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,hydrochloride
CAS Number: 2328-12-3
Molecular Formula: C₁₁H₁₆ClNO₂
Molecular Weight: 229.703
Catalog: Pharmaceutical intermediate Heterocyclic compound Isoquinoline compound
Create Date: 2019-01-10 15:58:52
Modify Date: 2024-01-18 18:28:23

Name	6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,hydrochloride
Synonyms	6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride (1:1) EINECS 251-223-7 6,7-dimethoxy-1,2,3,4-tetrahydroisochinoline hydrochloride MFCD00012744 6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline Hydrochloride 1,2,3,4-Tetrahydro-6,7-dimethoxyisoquinoline hydrochloride Heliamine hydrochloride 6,7-Dimethoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1) 1,2,3,4-tetrahydro-6,7-dimethoxylsoquinoline hydrochloride 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline,chloride 1,2,3,4-tetrahydro-6,7-dimethoxy-,hydrochloride

Density	1.071g/cm3
Boiling Point	314.9ºC at 760 mmHg
Melting Point	260-265 °C(lit.)
Molecular Formula	C₁₁H₁₆ClNO₂
Molecular Weight	229.703
Flash Point	124.7ºC
Exact Mass	229.086960
PSA	30.49000
LogP	2.48030
Vapour Pressure	0.000451mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NX5017980

CHEMICAL NAME :: Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride

CAS REGISTRY NUMBER :: 2328-12-3

LAST UPDATED :: 199009

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H15-N-O2.Cl-H

MOLECULAR WEIGHT :: 229.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 272 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay)

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 88,1197,1968

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 160 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 62,165,1938

Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
WGK Germany	3
RTECS	NX5017980
HS Code	2933499090

26259-07-4

2328-12-3

Literature: US2008/33177 A1, ; Page/Page column 10-11 ;

50-00-0

120-20-7

~68%

2328-12-3

Literature: Zhu, Ju; Lu, Jiaguo; Zhou, Youjun; Li, Yaowu; Cheng, Jun; Zheng, Canhui Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 20 p. 5285 - 5289

109-87-5

120-20-7

~86%

2328-12-3

Literature: Stenlake; Waigh; Urwin; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 6 p. 508 - 514

7647-01-0

14429-07-3

1333-74-0

2328-12-3

Literature: Chem. Pharm. Bull. (Tokyo), , vol. 14, p. 1382 - 1388 B: B-Verb.14, 3.14.1, page 144 - 145

Precursor 4
50-00-0 120-20-7 109-87-5 7647-01-0
DownStream 10
52768-23-7 463-72-9 1745-07-9 15248-39-2
3382-18-1 82925-01-7 82925-02-8 621-84-1
31756-14-6 16620-96-5

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

56-41-7	108-65-6
56-35-9	64-17-5
67-56-1	108-88-3
141-78-6	1310-73-2
13463-67-7	1333-86-4