135525-71-2

135525-71-2 structure
135525-71-2 structure
  • Name: L 696229
  • Chemical Name: 3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-1H-pyridin-2-one
  • CAS Number: 135525-71-2
  • Molecular Formula: C17H18N2O2
  • Molecular Weight: 282.33700
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2016-05-19 22:09:51
  • Modify Date: 2024-01-05 22:11:27
  • L 696229 is a specific inhibitor ofhuman immunodeficiency virus type 1 (HIV-1)reverse transcriptase (RT) activity that possesses antiviral activity[1].

Name 3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-1H-pyridin-2-one
Synonyms 3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-pyridin-2(1H)-one
2-pyridinol,3-[2-(2-benzoxazolyl)ethyl]-5-ethyl-6-methyl
3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-2-(1H)-pyridinone
Description L 696229 is a specific inhibitor ofhuman immunodeficiency virus type 1 (HIV-1)reverse transcriptase (RT) activity that possesses antiviral activity[1].
Related Catalog
References

[1]. Goldman ME, et al. L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro. Antimicrob Agents Chemother. 1992;36(5):1019-1023.  

Density 1.149g/cm3
Boiling Point 496.5ºC at 760mmHg
Molecular Formula C17H18N2O2
Molecular Weight 282.33700
Flash Point 254.1ºC
Exact Mass 282.13700
PSA 59.15000
LogP 3.58440
Vapour Pressure 5.37E-10mmHg at 25°C
Index of Refraction 1.58

~93%

135525-71-2 structure

135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

135525-71-2 structure

135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

135525-71-2 structure

135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

135525-71-2 structure

135525-71-2

Literature: Hoffman; Smith; Rooney; Fisher; Wai; Thomas; Bamberger; Barnes; Williams; Jones; Olson; O'Brien; Goldman; Nunberg; Quintero; Schleif; Emini; Anderson Journal of Medicinal Chemistry, 1993 , vol. 36, # 8 p. 953 - 966

~%

135525-71-2 structure

135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

135525-71-2 structure

135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925