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1001754-59-1

1001754-59-1 structure
1001754-59-1 structure

Name 3-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid
Synonyms 1-boc-3-fluoropyrrolidine-3-carboxylic acid
1-(tert-butoxycarbonyl)-3-fluoropyrrolidine-3-carboxylic acid
Boiling Point 329.8±42.0°C at 760 mmHg
Molecular Formula C10H16FNO4
Molecular Weight 233.23700
Exact Mass 233.10600
PSA 66.84000
LogP 1.35800
Storage condition 2-8℃
HS Code 2933990090

~90%

1001754-59-1 structure

1001754-59-1

Literature: ARRAY BIOPHARMA INC.; GENENTECH, INC.; BLAKE, James, F.; CHEN, Huifen; CHICARELLI, Mark, Joseph; DEMEESE, Jason; GARREY, Rustam, Ferdinand; GAUDINO, John; GAZZARD, Lewis; KAUS, Robert J.; KINTZ, Samuel; MOHR, Peter J.; MORENO, David, A.; SCHWARZ, Jacob; SIEDEM, Christopher, S.; WALLACE, Eli, M. Patent: WO2013/20062 A1, 2013 ; Location in patent: Paragraph 00244 ; WO 2013/020062 A1

~71%

1001754-59-1 structure

1001754-59-1

Literature: Yarmolchuk, Vladimir S.; Mykhailiuk, Pavel K.; Komarov, Igor V. Tetrahedron Letters, 2011 , vol. 52, # 12 p. 1300 - 1302
Precursor  3

DownStream  0

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%