202114-53-2

202114-53-2 structure
202114-53-2 structure

Name (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylpentanoic acid
Synonyms L-Leucine-1-13C,N-Fmoc
N-(9-Fluorenylmethoxycarbonyl)-L-leucine-1-13C,L-Leucine-1-13C,N-Fmoc
MFCD00190328
Fmoc-D-Leu-OH
Leucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-Leu-OH-1-13C
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]leucine
Description Fmoc-leucine-13C is a 13C-labeled Boc-Glycine[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Density 1.2±0.1 g/cm3
Boiling Point 559.8±33.0 °C at 760 mmHg
Melting Point 152-156ºC(lit.)
Molecular Formula C2013CH23NO4
Molecular Weight 354.40
Flash Point 292.4±25.4 °C
Exact Mass 353.162720
PSA 75.63000
LogP 4.95
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.583
RIDADR NONH for all modes of transport
WGK Germany 3