30408-07-2

30408-07-2 structure

30408-07-2 structure

Name: JB002
Chemical Name: JB002
CAS Number: 30408-07-2
Molecular Formula: C₁₈H₁₅NO₃
Molecular Weight: 293.32
Catalog: Signaling Pathways Cytoskeleton Myosin
Create Date: 2023-04-09 18:22:49
Modify Date: 2023-04-09 18:22:49
JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].

Name	JB002

Description	JB002 is a myosin II inhibitor, with an IC50 of ≤10 μM. JB002 can be used for the research of muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cytoskeleton >> Myosin
Target	IC50: ≤10 μM (myosin II)[1]
In Vitro	JB002 在心脏和骨骼肌球蛋白之间表现出良好的选择性，但对非肌肉 IIB 没有可检测的活性[1]。
References	[1]. Smith JD, et, al. Isoform selectivities of novel 4-hydroxycoumarin imines as inhibitors of myosin II. Eur J Med Chem. 2022 Dec 12;247:115008.

Molecular Formula	C₁₈H₁₅NO₃
Molecular Weight	293.32