195158-85-1

195158-85-1 structure

195158-85-1 structure

Name: Vepalimomab
Chemical Name: Vepalimomab
CAS Number: 195158-85-1
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Inflammation/Immunology
Create Date: 2023-01-11 18:55:18
Modify Date: 2024-01-13 17:24:19
Vepalimomab (Anti-Human AOC3 Recombinant Antibody) is a monoclonal antibody that blocks vascular adhesion protein 1 (VAP-1). Vepalimomab has anti-inflammatory effects[1].

Name	Vepalimomab

Description	Vepalimomab (Anti-Human AOC3 Recombinant Antibody) is a monoclonal antibody that blocks vascular adhesion protein 1 (VAP-1). Vepalimomab has anti-inflammatory effects[1].
Related Catalog	Research Areas >> Inflammation/Immunology
In Vivo	Vepalimomab (Anti-human-VAP-1 mAb 1B2; 3 mg/kg; i.v; once) 显示在发炎的皮肤和滑膜中上调[2]。 Vepalimomab (3 mg/kg; i.v) 显示初始快速分布相在猪体内的半衰期为 26 分钟，相应的消除相半衰期为 431 分钟[2]。
References	[1]. Petri J Vainio, et al. Safety of blocking vascular adhesion protein-1 in patients with contact dermatitis. Basic Clin Pharmacol Toxicol. 2005 Jun;96(6):429-35. [2]. K Jaakkola, et al. In vivo detection of vascular adhesion protein-1 in experimental inflammation. Am J Pathol. 2000 Aug;157(2):463-71.

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