928712-10-1

928712-10-1 structure

Name: HG106
Chemical Name: Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-
CAS Number: 928712-10-1
Molecular Formula: C₁₅H₁₃ClN₄O₂
Molecular Weight: 316.74
Catalog: Research Areas Cancer
Create Date: 2022-03-13 14:29:57
Modify Date: 2024-04-06 21:56:47
HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].

Name	Acetamide, 2-chloro-N-[2-(4-methoxyphenyl)-2H-benzotriazol-5-yl]-

Description	HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis. HG106 can be used for the research of KRAS-mutant lung adenocarcinoma[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.

Molecular Formula	C₁₅H₁₃ClN₄O₂
Molecular Weight	316.74