Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: BIBU1361
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

793726-84-8

793726-84-8 structure
793726-84-8 structure
  • Name: BIBU1361
  • Chemical Name: N-(3-chloro-4-fluorophenyl)-6-[4-(diethylaminomethyl)piperidin-1-yl]pyrimido[5,4-d]pyrimidin-4-amine,dihydrochloride
  • CAS Number: 793726-84-8
  • Molecular Formula: C22H27ClFN7
  • Molecular Weight: 443.95
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2016-07-22 07:26:06
  • Modify Date: 2024-01-27 21:58:59
  • BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].

Name N-(3-chloro-4-fluorophenyl)-6-[4-(diethylaminomethyl)piperidin-1-yl]pyrimido[5,4-d]pyrimidin-4-amine,dihydrochloride
Synonyms bibu 1361 dihydrochloride
bibu 1361
Description BIBU1361 induces apoptosis and inhibits autophagy. BIBU1361 inhibits pro-survival pathways Akt/mTOR and gp130/JAK/STAT3, and decreased levels of pro-inflammatory cytokine IL-6[1].
Related Catalog
References

[1]. Ruchi Ghildiyal, et, al. EGFR inhibitor BIBU induces apoptosis and defective autophagy in glioma cells. Mol Carcinog. 2013, 52,12.  

Boiling Point 663.5ºC at 760 mmHg
Molecular Formula C22H27ClFN7
Molecular Weight 443.95
Flash Point 355.1ºC
Exact Mass 515.15300
PSA 70.07000
LogP 6.25610