1438272-42-4

1438272-42-4 structure

Name: MBX2329
Chemical Name: MBX2329
CAS Number: 1438272-42-4
Molecular Formula: C₁₆H₂₆ClNO
Molecular Weight: 283.837
Create Date: 2020-10-11 18:17:26
Modify Date: 2023-02-04 19:09:51
MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains[1].

Name	MBX2329
Synonyms	1-[2-(2-Ethylphenoxy)ethyl]azepane hydrochloride (1:1) 1H-Azepine, 1-[2-(2-ethylphenoxy)ethyl]hexahydro-, hydrochloride (1:1)

Description	MBX2329, a potent influenza virus inhibitor, specifically inhibits hemagglutinin (HA)-mediated viral entry with HIV/HA(H5) displaying IC90 of 8.6 μM. MBX2329 inhibits a wide spectrum of influenza A viruses, which includes the 2009 pandemic influenza virus A/H1N1/2009, highly pathogenic avian influenza (HPAI) virus A/H5N1, and oseltamivir-resistant A/H1N1 strains[1].
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Infection
References	[1]. Basu A, et al. New small molecule entry inhibitors targeting hemagglutinin-mediated influenza a virus fusion. J Virol. 2014;88(3):1447-1460.