2138838-56-7

2138838-56-7 structure

2138838-56-7 structure

Name: HS79
Chemical Name: HS79
CAS Number: 2138838-56-7
Molecular Formula: C₁₉H₂₂N₄S
Molecular Weight: 338.47
Catalog: Signaling Pathways Metabolic Enzyme/Protease Fatty Acid Synthase (FAS)
Create Date: 2019-02-09 11:12:05
Modify Date: 2024-01-06 13:17:51
HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

Name	HS79

Description	HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Fatty Acid Synthase (FAS) Research Areas >> Cancer
Target	FASN[1]
In Vitro	Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].
References	[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

Molecular Formula	C₁₉H₂₂N₄S
Molecular Weight	338.47