41107-56-6

41107-56-6 structure

Name: 2′,3′-Dideoxy-3′-fluorouridine
Chemical Name: 2',3'-dideoxy-3'-fluorouridine
CAS Number: 41107-56-6
Molecular Formula: C₉H₁₁FN₂O₄
Molecular Weight: 230.19
Catalog: Biochemical Nucleoside drugs Deoxynucleotides and their analogues
Create Date: 2018-12-28 22:55:21
Modify Date: 2024-01-09 17:05:22
2′,3′-Dideoxy-3′-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2',3'-dideoxy-3'-fluorouridine
Synonyms	1-(2,3-dideoxy-3-fluoropentofuranosyl)pyrimidine-2,4(1H,3H)-dione Fddurd URIDINE,2',3'-DIDEOXY-3'-FLUORO 2,4(1H,3H)-Pyrimidinedione, 1-(2,3-dideoxy-3-fluoropentofuranosyl)- 5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidine)-3-fluoro-2-hydroxymethyltetrahydrofuran 1-(2,3-Dideoxy-3-fluoropentofuranosyl)-2,4(1H,3H)-pyrimidinedione EINECS 415-360-8 3'-FLUORO-2',3'-DIDEOXYURIDINE MFCD00192015 2'3'-dideoxy-3'-fluorouridine

Description	2′,3′-Dideoxy-3′-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Symbol	GHS08
Signal Word	Warning
Hazard Statements	H341
Precautionary Statements	P281
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R68
Safety Phrases	22-36/37
RIDADR	NONH for all modes of transport
WGK Germany	1
HS Code	29349990