37739-05-2

37739-05-2 structure

Name: ccpa
Chemical Name: 2-Chloro-N6-cyclopentyl Adenosine
CAS Number: 37739-05-2
Molecular Formula: C₁₅H₂₀ClN₅O₄
Molecular Weight: 369.80
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-04-24 08:00:00
Modify Date: 2024-01-05 18:25:21
CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Chloro-N6-cyclopentyl Adenosine
Synonyms	2-Chloro-N-cyclopentyladenosine 2-Chloro-N6-cyclopentyladenosine 2-Chloro-N6-cyclopentyladenosine,2-Chloro-N-cyclopentyladenosine

Description	CCPA (2-Chloro-N6-cyclopentyladenosine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. [2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 44,1305,1994

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	AU7357555