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4663-83-6

4663-83-6 structure
4663-83-6 structure
  • Name: Carbamic acid,N-(phenylmethyl)-, 2-hydroxyethyl ester
  • Chemical Name: 2-hydroxyethyl N-benzylcarbamate
  • CAS Number: 4663-83-6
  • Molecular Formula: C10H13NO3
  • Molecular Weight: 195.21500
  • Create Date: 2018-07-01 13:12:09
  • Modify Date: 2024-01-16 18:00:14
  • Buramate exhibits neuroprotective and anticonvulsant activities.

Name 2-hydroxyethyl N-benzylcarbamate
Synonyms AC-601
Buramate
Hyamate
Buramat
2-Benzylcarbamoyloxy-aethanol
2-Hydroxyethyl benzylcarbamate
Description Buramate exhibits neuroprotective and anticonvulsant activities.
Related Catalog
Density 1.182 g/cm3
Boiling Point 375.8ºC at 760mmHg
Molecular Formula C10H13NO3
Molecular Weight 195.21500
Flash Point 181.1ºC
Exact Mass 195.09000
PSA 58.56000
LogP 1.29600
Index of Refraction 1.542

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EY8747000
CHEMICAL NAME :
Carbamic acid, benzyl-, 2-hydroxyethyl ester
CAS REGISTRY NUMBER :
4663-83-6
BEILSTEIN REFERENCE NO. :
2838813
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C10-H13-N-O3
MOLECULAR WEIGHT :
195.24
WISWESSER LINE NOTATION :
Q2OVM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
850 mg/kg
TOXIC EFFECTS :
Brain and Coverings - recordings from specific areas of CNS Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 127,220,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 9,390,1951
HS Code 2924299090

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4663-83-6 structure

4663-83-6

Literature: Delaby et al. Bulletin de la Societe Chimique de France, 1956 , p. 831,835 Full Text Show Details Viard; Piganiol Chim.et Ind.Sonderband 23.Congr.int.Chim.ind.Mailand, 1950 , p. 233,236 Full Text Show Details Hazard et al. Annales Pharmaceutiques Francaises, 1951 , vol. 9, p. 390,396

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4663-83-6 structure

4663-83-6

Detail
Literature: Shivarkar, Anandkumar B.; Gupte, Sunil P.; Chaudhari, Raghunath V. Synlett, 2006 , # 9 p. 1374 - 1378
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%