63717-27-1

63717-27-1 structure
63717-27-1 structure

Name 2-(3-aminopropylamino)ethylsulfanylphosphonic acid,hydrate
Synonyms Amifostine hydrate
amifostine monohydrate
Amifostinum
Amifostina
Boiling Point 441.7ºC at 760 mmHg
Molecular Formula C5H17N2O4PS
Molecular Weight 232.23800
Flash Point 220.9ºC
Exact Mass 232.06500
PSA 139.92000
LogP 0.77760

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TE6493000
CHEMICAL NAME :
Phosphorothioic acid, S-(2-((3-aminopropyl)amino)ethyl) ester, hydrate
CAS REGISTRY NUMBER :
63717-27-1
LAST UPDATED :
199009
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H15-N2-O3-P-S.H2-O
MOLECULAR WEIGHT :
232.27
WISWESSER LINE NOTATION :
Z3M2SPQQO &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 12,236,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
375 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 9,911,1966

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63717-27-1 structure

63717-27-1

Literature: WO2007/53730 A1, ; Page/Page column 14-15 ;
Precursor  1

DownStream  0