SM-2470

Names

[ Name ]:
SM-2470

Biological Activity

[Description]:

SM-2470 is a potent α1-adrenoceptor antagonist, has sympathetic nerve activity in anesthetized rats[1]. SM-2470 is an antihypertensive agent. SM-2470 exhibits hypocholesterolaemic effect by the inhibition of cholesterol absorption related to the reduction of cholesterol solubilization[2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[References]

[1]. M Yoshioka, et al. Effect of SM-2470, a newly synthetized alpha 1-adrenoceptor antagonist, on sympathetic nerve activity in anesthetized rats. Arch Int Pharmacodyn Ther. May-Jun 1988;293:162-74.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₃₀ClN₅O₃

[ Molecular Weight ]:
459.97

Related Compounds

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