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Echinocystic acid 28-O-beta-D-glucoside

Names

[ CAS No. ]:
99633-30-4

[ Name ]:
Echinocystic acid 28-O-beta-D-glucoside

Biological Activity

[Description]:

Echinocystic acid 28-O-β-D-glucoside is a metabolite of Echinocystic acid by microbial oxidation and glucosidation. Echinocystic acid 28-O-β-D-glucoside is a tissue factor pathway inhibitor, with an IC50 of 10.61 nM[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Others >> Others

[In Vitro]

Echinocystic acid 28-O-β-D-glucoside inhibits tissue factor (TF) procoagulant activities in human THP-1 cells stimulated by lipopolysaccharide, with an IC50 of 10.61 nM[1].

[References]

[1]. Wang WW, et, al. Microbial hydroxylation and glycosylation of pentacyclic triterpenes as inhibitors on tissue factor procoagulant activity. Bioorg Med Chem Lett. 2017 Feb 15;27(4):1026-1030.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H58O9

[ Molecular Weight ]:
634.84

Related Compounds