Adenosine 5'-triphosphate disodium salt

Names

[ CAS No. ]:
987-65-5

[ Name ]:
Adenosine 5'-triphosphate disodium salt

[Synonym ]:
Adenosine, 5'-(tetrahydrogen triphosphate), sodium salt (1:2)
Adetphos
ATP disodium salt
Adinosine Triphosphate Disodium
UNII-5L51B4DR1G
ATP-Disodium Salt
Adenosine 5'-(tetrahydrogen triphosphate), disodium salt
adenosine triphosphate disodium
Disodium 5'-O-(hydroxy{[hydroxy(phosphonatooxy)phosphoryl]oxy}phosphoryl)adenosine
EINECS 213-579-1
ATP disodium
Adenosine 5'-(disodium triphosphate)
Trinosin
Adenosine 5-Triphosphate Disodium Salt
Disodium adenosine 5'-triphosphate
Adenosine 5'-triphosphate disodium salt
Atenen
Circulen
Adenosine 5'-triphosphate, disodium salt
Adenosine-5'-triphosphate disodium salt
Disodium 5'-O-[({hydroxy[(hydroxyphosphinato)oxy]phosphoryl}oxy)phosphinato]adenosine
Disodium adenosine triphosphate
MFCD00080339
DISODIUM ATP
ATP
ATP (disodium salt)

Biological Activity

[Description]:

ATP is a phosphate-group donor for substrate activation in metabolic reactions and the coenzyme for a large number of kinases.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> P2X Receptor

Natural Products >> Alkaloid

Research Areas >> Metabolic Disease

[References]

[1]. Gordon, J.L., Extracellular ATP: effects, sources and fate. Biochem J, 1986. 233(2): p. 309-19.

[2]. Guibert, C., et al., Dependence of P2-nucleotide receptor agonist-mediated endothelium-independent relaxation on ectonucleotidase activity and A2A-receptors in rat portal vein. Br J Pharmacol, 1998. 123(8): p. 1732-40.

[3]. Burnstock, G., Historical review: ATP as a neurotransmitter. Trends Pharmacol Sci, 2006. 27(3): p. 166-76.

[Related Small Molecules]

KN-62 | A-740003 | A 438079 | af-353 | AZD9056 hydrochloride | PSB-12062 | A-317491 | A 804598 | A 839977 | Gefapixant | GW791343 | Lappaconitine | CE-224535 | JNJ-54175446

Chemical & Physical Properties

[ Density]:
2.63g/cm3

[ Boiling Point ]:
951.4ºC at 760mmHg

[ Melting Point ]:
188-190ºC

[ Molecular Formula ]:
C₁₀H₁₄N₅Na₂O₁₃P₃

[ Molecular Weight ]:
551.145

[ Exact Mass ]:
550.959656

[ PSA ]:
314.22000

[ Water Solubility ]:
H2O: 50 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7417000

CHEMICAL NAME :: Adenosine 5'-(tetrahydrogen triphosphate), disodium salt

CAS REGISTRY NUMBER :: 987-65-5

LAST UPDATED :: 199706

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H14-N5-O13-P3.2Na

MOLECULAR WEIGHT :: 551.18

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQO&OPQO&OPQQO &-NA- 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 266 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,20,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9988 No. of Facilities: 45 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 308 (estimated) No. of Female Employees: 209 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AU7417000

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