2-Thio-PAF

Names

[ Name ]:
2-Thio-PAF

[Synonym ]:
1-Hexadecyl-2-thioacetyl-2-deoxyglycerophosphocholine
2-thio PAF
Ethanaminium, 2-[[[(2R)-2-(acetylthio)-3-(hexadecyloxy)propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
(2R)-2-(Acetylsulfanyl)-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate
1-hexadecyl-2-thioacetyl-2-deoxy-sn-glycero-3-phosphocholine
1-O-hexadecyl-2-thioacetyl-2-deoxy-sn-glycero-3-phosphocholine

Biological Activity

[Description]:

2-Thio-PAF, a synthetic analog of PAF, is used in a colorimetric assay for PAF acetylhydrolases[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

2-Thio-PAF induced platelet-aggregation that was inhibited by previous incubation of the substrate with salivary gland homogenates or saliva[1].

[References]

[1]. Côrte-Real R, et al. The activity of platelet activating factor-acetyl hydrolase (PAF-AH) in the salivary glands of Rhodnius prolixus. J Insect Physiol. 2011 Jun;57(6):825-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₅₄NO₆PS

[ Molecular Weight ]:
539.749

[ Exact Mass ]:
539.340942

[ PSA ]:
120.00000

[ LogP ]:
4.76

Safety Information

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

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