cFMS Receptor Inhibitor IV

Names

[ CAS No. ]:
959626-45-0

[ Name ]:
cFMS Receptor Inhibitor IV

[Synonym ]:
cFMS Receptor Inhibitor IV
5-Cyano-N-(2,5-di-1-piperidinylphenyl)-2-furancarboxamide
5-cyano-N-(2,5-di(piperidin-1-yl)phenyl)furan-2-carboxamide

Biological Activity

[Description]:

cFMS Receptor Inhibitor IV (Compound 42) is a potent cFMS inhibitor with an IC50 of 0.017 μM[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> c-Fms

[Target]

IC50: 0.017 μM (cFMS)[1]

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
530.5ºC at 760 mmHg

[ Molecular Formula ]:
C22H26N4O2

[ Molecular Weight ]:
378.46700

[ Flash Point ]:
274.6ºC

[ Exact Mass ]:
378.20600

[ PSA ]:
72.51000

[ LogP ]:
4.58718

[ Index of Refraction ]:
1.63


Related Compounds