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XL147

Names

[ CAS No. ]:
956958-53-5

[ Name ]:
XL147

[Synonym ]:
XL 147
XL-147
XL147
PI3K inhibitor X
SAR245408

Biological Activity

[Description]:

Pilaralisib analogue (XL147 analogue) is a representative and selective PI3Kα inhibitor extracted from patent WO2012006552A1, Compound 147 in Table 1.

[Related Catalog]:

Research Areas >> Cancer

[Target]

PI3K-alpha


[References]

[1]. Carlos L. Arteaga, et al. Combinations of kinase inhibitors for the treatment of cancer. WO 2012006552 A1.


[Related Small Molecules]

3-Methyladenine | LY294002 | Wortmannin | Alpelisib (BYL719) | BKM120 | Eganelisib(IPI-549) | BAY 80-6946 (Copanlisib) | Idelalisib (CAL-101) | Dactolisib (BEZ235) | Quercetin | SAR-405 | GDC-0941 | 740 Y-P | LY3023414 | 1,3-Dicaffeoylquinic acid

Chemical & Physical Properties

[ Density]:
1.538

[ Molecular Formula ]:
C21H16N6O2S2

[ Molecular Weight ]:
448.52100

[ Exact Mass ]:
448.07800

[ PSA ]:
149.61000

[ LogP ]:
5.06300

[ Storage condition ]:
-20℃

Related Compounds

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