PQ1 Succinate
Names
[ CAS No. ]:
955995-51-4
[ Name ]:
PQ1 Succinate
[Synonym ]:
N1-[6-Methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-1,3-propanediamine butanedioic acid salt
PQ1 succinic acid salt
1,3-Propanediamine, N1-[6-methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl]-, butanedioate (1:1)
Succinic acid - N-{6-methoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]-8-quinolinyl}-1,3-propanediamine (1:1)
MFCD22666397
PQ1 succinate
Chemical & Physical Properties
[ Molecular Formula ]:
C25H28F3N3O6
[ Molecular Weight ]:
523.502
[ Exact Mass ]:
523.192993
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Cancer Sci. Ther. 4(11) , 371-378, (2012)
Cisplatin is one of the most widely used anti-cancer drugs due to its ability to damage DNA and induce apoptosis. However, increasing reports of side effects and drug resistance indicate the limitatio...
PQ1, a quinoline derivative, induces apoptosis in T47D breast cancer cells through activation of caspase-8 and caspase-9.Apoptosis 18(9) , 1071-82, (2013)
Apoptosis, a programmed cell death, is an important control mechanism of cell homeostasis. Deficiency in apoptosis is one of the key features of cancer cells, allowing cells to escape from death. Acti...
The effect of the PQ1 anti-breast cancer agent on normal tissues.Anticancer Drugs 23(9) , 897-905, (2012)
Gap junctions are intercellular channels connecting adjacent cells, allowing cells to transport small molecules. The loss of gap junctional intercellular communication (GJIC) is one of the important h...