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C6 NBD Glucosylceramide (d18:1/6:0)

Names

[ CAS No. ]:
94885-03-7

[ Name ]:
C6 NBD Glucosylceramide (d18:1/6:0)

Biological Activity

[Description]:

C6 NBD Glucosylceramide is a glucosylceramide fluorescent derivative (Ex=466 nm, Em=535 nm). C6 NBD Glucosylceramide can be used to study the metabolism and internalization of glucosylceramide and also for the determination of glucosyl ceramide synthase activity[1][2][3].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Kok JW, et al. Salvage of glucosylceramide by recycling after internalization along the pathway of receptor-mediated endocytosis. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9896-900.

[2]. Hayashi Y, et al. A sensitive and reproducible assay to measure the activity of glucosylceramide synthase and lactosylceramide synthase using HPLC and fluorescent substrates. Anal Biochem. 2005 Oct 15;345(2):181-6.

[3]. di Bartolomeo S, et al. Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells. Biochem Biophys Res Commun. 2001 Oct 19;288(1):269-74.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H59N5O11

[ Molecular Weight ]:
737.88

[ Storage condition ]:
−20°C

Safety Information

[ WGK Germany ]:
3

Related Compounds