Capsiconiate(solution)

Names

[ Name ]:
Capsiconiate(solution)

[Synonym ]:
capsiconiate
(2E)-3-(4-Hydroxy-3-methoxyphenyl)-2-propen-1-yl (6E)-8-methyl-6-nonenoate
6-Nonenoic acid, 8-methyl-, (2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-yl ester, (6E)-

Biological Activity

[Description]:

Capsiconiate (Coniferyl (E)-8-methyl-6-nonenoate) is a TRPV1 agonist (EC50= 3.2 μM). Capsiconiate can be used to study TRPV1-mediated diseases such as pain, inflammation, and epilepsy(EC50= 3.2 μM)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[Target]

EC50: 3.2 μM (TRPV1)[1].

[References]

[1]. Kobata K, et al. Isolation of coniferyl esters from Capsicum baccatum L., and their enzymatic preparation and agonist activity for TRPV1. Phytochemistry. 2008 Mar;69(5):1179-84.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
472.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₈O₄

[ Molecular Weight ]:
332.43

[ Flash Point ]:
159.6±22.2 °C

[ Exact Mass ]:
332.198761

[ LogP ]:
5.46

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.539

Related Compounds

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