Piroxicam D3

Names

[ CAS No. ]:
942047-64-5

[ Name ]:
Piroxicam D3

[Synonym ]:
Roxicam-d3
Baxo-d3
Artroxicam-d3
Roxiden-d3
Sasulen-d3
Solocalm-d3
Bruxicam-d3
Caliment-d3
Piroxicam-d3

Biological Activity

[Description]:

Piroxicam D3 (CP-16171 D3) is deuterium labeled Piroxicam. Piroxicam is a non-steroidal anti-inflammatory drugs, acts as a COX inhibitor, with IC50s of 47, 25 μM for human monocyte COX-1 and COX-2, respectively [1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Kato M, et al. Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. J Pharm Pharmacol. 2001 Dec;53(12):1679-85.

Chemical & Physical Properties

[ Density]:
1.577g/cm3

[ Melting Point ]:
193-195ºC

[ Molecular Formula ]:
C₁₅H₁₀D₃N₃O₄S

[ Molecular Weight ]:
331.34600

[ Exact Mass ]:
331.06300

[ PSA ]:
111.47000

[ LogP ]:
3.24920

[ Index of Refraction ]:
1.714

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
26-36

[ RIDADR ]:
UN 2811 6.1 / PGIII