5-Bromo-6-chloro-3-indolyl-beta-D-galactoside

Names

[ Name ]:
5-Bromo-6-chloro-3-indolyl-beta-D-galactoside

[Synonym ]:
MFCD00216824
5-BROMO-6-CHLORO-3-INDOLYL-B-D-*GALACTOPYRANOSIDE
5-Bromo-6-chloro-1H-indol-3-yl β-L-glucopyranoside
β-L-Glucopyranoside, 5-bromo-6-chloro-1H-indol-3-yl
Mag-Gal,Magenta-Gal
mag-gal
5-Bromo-6-chloro-3-indolyl-beta-D-galactoside
RED-GAL
MAGENTA-GAL

Biological Activity

[Description]:

5-Bromo-6-chloro-3-indolyl β-D-Galactopyranoside (contains ca. 10% Ethyl Acetate) (5-Bromo-6-chloro-3-indolyl-beta-D-galactoside) is a chromogenic substrate of β-galactosidase (β-gal)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Michael Simon Krämer, et al. Analysis of Gene Expression Using lacZ Reporter Mouse Lines. Methods Mol Biol. 2021;2224:29-45.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
673.9±55.0 °C at 760 mmHg

[ Melting Point ]:
187-191ºC

[ Molecular Formula ]:
C₁₄H₁₅BrClNO₆

[ Molecular Weight ]:
408.629

[ Flash Point ]:
361.3±31.5 °C

[ Exact Mass ]:
406.977112

[ PSA ]:
115.17000

[ LogP ]:
0.62

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.732

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Xenopus laevis FGF receptor substrate 3 (XFrs3) is important for eye development and mediates Pax6 expression in lens placode through its Shp2-binding sites.

Dev. Biol. 397(1) , 129-39, (2015)

Members of the fibroblast growth factor (FGF) family play important roles during various developmental processes including eye development. FRS (FGF receptor substrate) proteins bind to FGFR and serve...

Zic1 controls placode progenitor formation non-cell autonomously by regulating retinoic acid production and transport.

Nat. Commun. 6 , 7476, (2015)

All cranial placode progenitors arise from a common precursor field anterior to the neural plate, the pre-placodal region (PPR). We showed that transcription factor Zic1, expressed at the anterior neu...

Characterization of a heat resistant beta-glucosidase as a new reporter in cells and mice.

BMC Biol. 8 , 89, (2010)

Reporter genes are widely used in biology and only a limited number are available. We present a new reporter gene for the localization of mammalian cells and transgenic tissues based on detection of t...