<Suppliers Price>

TG-46

Names

[ CAS No. ]:
936091-15-5

[ Name ]:
TG-46

[Synonym ]:
EX-8668
RS0111
3-[(5-Methyl-2-{[4-(4-morpholinylmethyl)phenyl]amino}-4-pyrimidinyl)amino]-N-(2-methyl-2-propanyl)benzenesulfonamide
Benzenesulfonamide,N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]
Benzenesulfonamide, N-(1,1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-morpholinylmethyl)phenyl]amino]-4-pyrimidinyl]amino]-
N-tert-butyl-3-(5-methyl-2-(4-(morpholinomethyl)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide
TG-46

Biological Activity

[Description]:

JAK-IN-35 (compound TG46) is a JAK2 inhibitor that canb be used in cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK

[References]

[1]. Wenge Zhu, et al. Combination therapy for treating cancer. Patent WO2018187485A1.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
687.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H34N6O3S

[ Molecular Weight ]:
510.652

[ Flash Point ]:
369.6±34.3 °C

[ Exact Mass ]:
510.241302

[ PSA ]:
120.09000

[ LogP ]:
1.83

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.621

Related Compounds