Fmoc-Tyr-OH

Names

[ Name ]:
Fmoc-Tyr-OH

[Synonym ]:
9-fluorenylmethyloxycarbonyl tyrosine
FMOC-TYR-OH
FMOC-L-TYR-OH
FMOC-L-TYROSINE
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine
N-FMOC-L-TYROSINE
Fmoc-L-Tyrsine
FMOC-TYROSINE
Fmoc-yrosine
MFCD00134890
Fmoc-Tyrosine-OH
N-Fmoc-L-tyrosine-OH
L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
FMOC-TYR

Biological Activity

[Description]:

Fmoc-Tyr-OH is a tyrosine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.336g/cm3

[ Boiling Point ]:
672.6ºC at 760 mmHg

[ Melting Point ]:
180 - 185ºC (Decomposes)

[ Molecular Formula ]:
C₂₄H₂₁NO₅

[ Molecular Weight ]:
403.42700

[ Flash Point ]:
360.6ºC

[ Exact Mass ]:
403.14200

[ PSA ]:
95.86000

[ LogP ]:
4.31750

[ Index of Refraction ]:
-22.0 ° (C=1， DMF)

[ Storage condition ]:
2~8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Aspartate-modified doxorubicin on its N-terminal increases drug accumulation in LAT1-overexpressing tumors.

Cancer Sci. 106 , 747-56, (2015)

L-type amino acid transporter 1 (LAT1), overexpressed on the membrane of various tumor cells, is a potential target for tumor-targeting therapy. This study aimed to develop a LAT1-mediated chemotherap...

Design and synthesis of newN-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents

Eur. J. Med. Chem. 44 , 1933-40, (2009)

Twenty-four new dipeptide analogs ( 1– 24) of aurantiamide acetate were designed, synthesized, and assayed for effects on superoxide anion generation and elastase release by human neutrophils in respo...