GerMacrone 4,5-epoxide

Names

[ Name ]:
GerMacrone 4,5-epoxide

[Synonym ]:
11-Oxabicyclo[8.1.0]undec-6-en-4-one, 6,10-dimethyl-3-(1-methylethylidene)-, (1S,6E,10S)-
(1S,6E,10S)-3-Isopropylidene-6,10-dimethyl-11-oxabicyclo[8.1.0]undec-6-en-4-one

Biological Activity

[Description]:

Germacrone 4,5-epoxide is a sesquiterpene that can be isolated from Curcuma cf. viridiflora. Germacrone 4,5-epoxide has excellent anti-leukemic activities[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
340.8±41.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂O₂

[ Molecular Weight ]:
234.33

[ Flash Point ]:
139.5±21.2 °C

[ Exact Mass ]:
234.161987

[ PSA ]:
29.60000

[ LogP ]:
3.14

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.502

Related Compounds

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