Glutathione-monoethyl ester (reduced)

Names

[ Name ]:
Glutathione-monoethyl ester (reduced)

[Synonym ]:
GSH-MEE
Glutathione monoethyl ester
Glutathione reduced ethyl ester
GSH monoethylester
Ethyl L-γ-glutamyl-L-cysteinylglycinate
Glycine, L-γ-glutamyl-L-cysteinyl-, ethyl ester
|A-Glu-Cys-Gly-OEt

Biological Activity

[Description]:

Glutathione ethyl ester is a cell-permeable GSH donor and provides an efficient supply of GSH to the oocyte. Glutathione ethyl ester shows positive effect on the?in?vitro?production of embryos by enhancement of the antioxidative defense[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

IC50：GSH[1]

[References]

[1]. F Magata, et al. Glutathione ethyl ester improved the age-induced decline in the developmental competence of bovine oocytes. Theriogenology. 2021 Jun:167:37-43.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
644.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₂H₂₁N₃O₆S

[ Molecular Weight ]:
335.38

[ Flash Point ]:
343.5±31.5 °C

[ Exact Mass ]:
335.115112

[ PSA ]:
186.62000

[ LogP ]:
0.00

[ Vapour Pressure ]:
0.0±4.1 mmHg at 25°C

[ Index of Refraction ]:
1.536

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

PRIMA-1Met induces myeloma cell death independent of p53 by impairing the GSH/ROS balance.

Blood 124(10) , 1626-36, (2014)

The aim of this study was to assess the efficiency of p53 reactivation and induction of massive apoptosis (PRIMA-1(Met)) in inducing myeloma cell death, using 27 human myeloma cell lines (HMCLs) and 2...

Dual-targeting of aberrant glucose metabolism in glioblastoma.

J. Exp. Clin. Cancer Res 34 , 14, (2015)

Glioblastoma (GBM) is the most common and malignant primary brain tumor. In contrast to some other tumor types, aberrant glucose metabolism is an important component of GBM growth and chemoresistance....

Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes.

Am. J. Physiol. Lung Cell. Mol. Physiol. 307(5) , L364-73, (2014)

This study assessed the effect of extended exposure to cigarette smoke extract (CSE) on tissue repair functions in lung fibroblasts. Human fetal (HFL-1) and adult lung fibroblasts were exposed to CSE ...

Related Compounds

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