D-Cysteine

Names

[ CAS No. ]:
921-01-7

[ Name ]:
D-Cysteine

[Synonym ]:
(2S)-2-amino-3-mercaptopropanoic acid
S-cysteine
(D,L)-H-Cys-OH
D-Cystein
MFCD00066461
D-Amino-3-mercaptopropionic acid
(S)-2-amino-3-mercaptopropanoic acid
(2S)-2-amino-3-sulfanylpropanoic acid
EINECS 213-062-0
(S)-2-Amino-3-mercaptopropionic acid
Cysteine,D
2-amino-3-sulfopropionic acid
D-Zystein
Cysteine, D-
H-D-Cys-OH

Biological Activity

[Description]:

D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of Escherichia coli growth. D-cysteine is mediated by D-amino acid oxidase to produce H2S and is a neuroprotectant against cerebellar ataxias. D-Cysteine could inhibit the growth and cariogenic virulence of dual-species biofilms formed by S. mutans and S. sanguinis[1][2][3].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Neurological Disease

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Human Endogenous Metabolite

[References]

[1]. Seki T. Availability of D-cysteine as a protectant for cerebellar neurons. Nihon Yakurigaku Zasshi. 2019;154(3):133-137.

[2]. Soutourina J, et al. Role of D-cysteine desulfhydrase in the adaptation of Escherichia coli to D-cysteine. J Biol Chem. 2001 Nov 2;276(44):40864-72.

[3]. Guo X1, et al. Effect of D-cysteine on dual-species biofilms of Streptococcus mutans and Streptococcus sanguinis. Sci Rep. 2019 Apr 30;9(1):6689.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
293.9±35.0 °C at 760 mmHg

[ Melting Point ]:
230ºC

[ Molecular Formula ]:
C₃H₇NO₂S

[ Molecular Weight ]:
121.158

[ Flash Point ]:
131.5±25.9 °C

[ Exact Mass ]:
121.019745

[ PSA ]:
102.12000

[ LogP ]:
0.23

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.550

[ Storage condition ]:
−20°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29309013

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29309013

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J. Pharm. Biomed. Anal. 100 , 58-63, (2014)

A liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometric method (LC-APCI-MS/MS) has been developed for the sensitive determination of antitumor thioproline and methyl...

Related Compounds

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