monoazidopropidium

Names

[ Name ]:
monoazidopropidium

[Synonym ]:
3-(3-amino-8-azido-6-phenylphenanthridin-5-ium-5-yl)propyl-diethyl-methylazanium dichloride
Monoazidopropidium

Biological Activity

[Description]:

Propidium monoazide is a photoreactive DNA-binding dye that preferentially binds to dsDNA. Propidium monoazide (PMA) prevents DNA from dead bacteria from being amplified during the PCR. PMA-PCR enhanced both the specificity and the sensitivity of PCR[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Mohamed Askar 1, et al. Propidium monoazide-polymerase chain reaction for detection of residual periprosthetic joint infection in two-stage revision. Mol Biol Rep. 2019 Dec;46(6):6463-6470.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₂Cl₂N₆

[ Molecular Weight ]:
511.48900

[ Exact Mass ]:
510.20700

[ PSA ]:
78.53000

[ LogP ]:
4.11776

Related Compounds

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