RBI-257 Maleate

Names

[ Name ]:
RBI-257 Maleate

[Synonym ]:
2-Pyridinamine, N-[1-[(4-iodophenyl)methyl]-4-piperidinyl]-N-methyl-3-(1-methylethoxy)-, (2Z)-2-butenedioate (1:1)
N-[1-(4-Iodobenzyl)-4-piperidinyl]-3-isopropoxy-N-methyl-2-pyridinamine (2Z)-2-butenedioate (1:1)
RBI 257 (maleate)

Biological Activity

[Description]:

RBI-257 maleate is a potent dopamine D4 receptor antagonist with a Ki value of 0.3 nM[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

[References]

[1]. Wilke RA, et, al. Dopamine D4 receptor mediated inhibition of potassium current in neurohypophysial nerve terminals. J Pharmacol Exp Ther. 1998 Feb;284(2):542-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₂IN₃O₅

[ Molecular Weight ]:
581.44

[ Exact Mass ]:
581.138672

Related Compounds

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